Research Interest
I am devoted to developing computational systems, algorithms, and artificial intelligence-driven tools to solve biological and medical problems. My research interests focus on computational proteomics, mass spectrometry, protein structure and function, and protein sequence analysis. Several ongoing research projects are developing machine learning models to identify various therapeutic peptides, devising hybrid quantitation algorithms for isobaric labeling-based proteomic experiments, and antibody-related studies such as paratope prediction. More recently, I have started working on natural language processing and its application on biomedical literature.
我的研究興趣為開發計算系統、演算法、以及人工智慧工具以解決生物醫學問題,研究領域包含了計算蛋白質體學、質譜儀、蛋白質結構及功能、以及蛋白質序列分析。目前幾個正在進行的研究計畫為開發機器學習方法來預測治療疾病用途的peptide序列,設計混合式標記化蛋白質體定量演算法,以及抗體相關研究例如paratope的預測,最近,我並開始從事自然語言處理以及它在生醫文獻的應用。
我的研究興趣為開發計算系統、演算法、以及人工智慧工具以解決生物醫學問題,研究領域包含了計算蛋白質體學、質譜儀、蛋白質結構及功能、以及蛋白質序列分析。目前幾個正在進行的研究計畫為開發機器學習方法來預測治療疾病用途的peptide序列,設計混合式標記化蛋白質體定量演算法,以及抗體相關研究例如paratope的預測,最近,我並開始從事自然語言處理以及它在生醫文獻的應用。
News
- 恭禧實驗室專題生蔡敦竹、楊景臣獲得亞大生醫系「112年畢業專題競賽」產業委員獎 (僅取一名) 2024/03. Congratulations to TC Tsai and CC Yang for winning the Industrial Committee Award of Senior Project Competition of BIME, Asia University.
- 恭禧實驗室專題生游荏捷獲得亞大生醫系「112年畢業專題競賽」第二名 2024/03. Congratulations to JC Yu for winning the second place in the Senior Project Competition of BIME, Asia University.
- The journal paper entitled "Unlocking the Secrets Behind Advanced Artificial Intelligence Language Models in De-Identifying Chinese-English Mixed Clinical Text,” was published in Journal of Medical Internet Research. (IF = 7.4, rank = 3/105) 2024/1
- 恭禧實驗室同學楊景臣錄取逢甲大學數據科學碩士學位學程 2024/1. Congratulations to CC Yang on admissions to the Master's program of Data Science, Feng Chia University.
- 恭禧實驗室同學李昀蓁錄取台灣科技大學資訊工程系碩士班 2023/12. Congratulations to YC Lee on admissions to the graduate program of Department of Computer Science and Information Engineering, National Taiwan University of Science and Technology.
- 恭禧實驗室同學游荏捷錄取中興大學基因體暨生物資訊學研究所 2023/11. Congratulations to JC You on admissions to the Graduate Institute of Genomics and Bioinformatics, National Chung Hsing University.
- A big welcome to Mr. Saptashwa Datta as he becomes a part of our lab team! 2023/9
- The journal paper entitled "Improving quantitation accuracy in isobaric-labeling mass spectrometry experiments with spectral library searching and feature-based peptide-spectrum match filter" was published in Scientific Reports (IF=4.996, rank = 8/110). 2023/8
- 恭禧實驗室專題生「陳思涵、郭邵淳」及「倪寬、游荏捷」兩組同學,獲得亞大生醫系「畢業專題競賽」並列第一名 2023/02. Congratulations to the two teams of students, SH Chen and SC Guo, as well as K Ni and JC You, for jointly winning the first place in the Senior Project Competition of BIME, Asia University.
- 恭禧實驗室三位同學陳思涵、郭劭淳、倪寬錄取中興大學基因體暨生物資訊學研究所 2022/11. Congratulations to SH Chen, SC Kuo, and K Ni on admissions to the Graduate Institute of Genomics and Bioinformatics, National Chung Hsing University.
- 實驗室發表文章 Sequence-based Prediction of Antimicrobial Peptides with CatBoost Classifier 於 IEEE International Conference on BioInformatics and BioEngineering (BIBE 2022) (游荏捷、倪寬為共同第一作者)
- 論文 Calibr improves spectral library search for spectrum-centric analysis of data independent acquisition proteomics 刊登於 Scientific Reports (IF=4.996, rank = 8/110)